Mutations in the GDD Motif of Rubella Virus Putative RNA-Dependent RNA Polymerase Affect Virus Replication
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منابع مشابه
Mutations in the retinoblastoma protein-binding LXCXE motif of rubella virus putative replicase affect virus replication.
The rubella virus (RV)-encoded protein NSP90, which contains the retinoblastoma protein (Rb)-binding motif LXCXE, interacts with Rb and RV replication is reduced in cells lacking Rb. Whether the LXCXE motif of RV NSP90 itself is essential for Rb binding and virus replication is not known. Therefore, in the present study, the functional role of this motif was investigated by site-directed mutage...
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ژورنال
عنوان ژورنال: Virology
سال: 2001
ISSN: 0042-6822
DOI: 10.1006/viro.2001.0939